Which bacteria causes post-streptococcal glomerulonephritis?
Post-streptococcal glomerulonephritis (PSGN) is an immunologically-mediated sequela of pharyngitis or skin infections caused by nephritogenic strains of Streptococcus pyogenes. S. pyogenes are also called group A Streptococcus or group A strep.
How can you differentiate between IgA nephropathy and post-streptococcal glomerulonephritis?
Differential Diagnosis IgA Nephropathy: usually occurs after an upper respiratory tract or gastrointestinal infection, but it differs from PSGN in the shorter latency period it takes to appear after the episode of infection. It can also be described as synpharyngitic hematuria- hematuria and infection coincide.
What causes post infectious glomerulonephritis?
PIGN can be caused by different kinds of germs, including bacteria and viruses. The most common type of PIGN is caused by a type of bacteria called streptococcus (strep). Post-streptococcal glomerulonephritis most often affects children 1-2 weeks after a streptococcal throat infection (“strep throat”).
Which antibody is found in post streptococcal glomerulonephritis?
The streptococcal antibodies measured include the following: Antistreptolysin (ASO) Antihyaluronidase (AHase)
Which antibodies is found in post streptococcal glomerulonephritis?
Which protein is responsible for the pathogenesis of post streptococcal glomerulonephritis?
(Nicholson, et al., 2000) found that 33 of 44 patients were seropositive for the Szp5058 fusion protein that was isolated from the causative streptococcal strain, and noted that the antiphagocytic properties of Szp proteins may play a role in the pathogenesis of glomerulonephritis.
What causes hypertension in post streptococcal glomerulonephritis?
Patients with acute GN have hypertension primarily due to sodium retention leading to fluid overload, as evidenced by suppression of the renin-angiotensin-aldosterone (RAAS) system.
What is the prognosis of poststreptococcal glomerulonephritis?
The prognosis of PSGN in children is very good; more than 90% of children make a full recovery. Adults with PSGN are more likely to have a worse outcome due to residual renal function impairment. 1
How can poststreptococcal glomerulonephritis be prevented?
Prevention. Unfortunately, antibiotics do not prevent PSGN from developing in persons with acute streptococcal infections (impetigo or pharyngitis). 1,2 Thus, it is important to prevent the primary group A streptococcal skin or pharyngeal infection. However, treating PSGN patients with antibiotics can stop a nephritogenic strain from
What are the causes of glomerulonephritis?
Glomerulonephritis is a kind of kidney disease. It involves damage to the glomeruli, tiny filters inside your kidneys. It’s caused by a variety of things, from infections to problems with the immune system.
What did the Doctor mean by glomerulonephritis?
What did the doctor mean by glomerulonephritis? Glomerulonephritis (gloe-mer-u-low-nuh-FRY-tis) is inflammation of the tiny filters in your kidneys (glomeruli). Glomeruli remove excess fluid, electrolytes and waste from your bloodstream and pass them into your urine. Glomerulonephritis can come on suddenly (acute) or gradually (chronic).